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Sulfadimethoxine

CHEMBL62193 Phase 4 Approved Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
310.3 g/mol
LogP
1.6
Phase
4

Sulfadimethoxine is a long-acting sulfonamide antibiotic used in veterinary medicine for treatment of coccidiosis and various bacterial infections, and historically used in human medicine for urinary tract infections and respiratory infections. Its prolonged half-life allows once-daily or less frequent dosing compared to short-acting sulfonamides. Like all sulfonamides, it inhibits dihydropteroate synthase to block bacterial folate synthesis.

Molecular Weight

310.3300 g/mol

LogP

1.60

TPSA

125.00 Ų

Lipinski RO5

Pass

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1

                

                

                
                

                    
InChI

                    
InChI=1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)

                

                

                

                    
                    

                        
Molecular Formula

                        
C12H14N4O4S

                    

                    
                    

                        
HBD / HBA

                        
2 / 8

                    

                    
                    

                        
Rotatable Bonds

                        
5

                    

                    
                    
                    

                        
Heavy Atoms

                        
21

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Frequently Asked Questions

                

                    
                    

                        
                        

                            
Sulfadimethoxine is a long-acting sulfonamide antibiotic used in veterinary medicine for treatment of coccidiosis and various bacterial infections, and historically used in human medicine for urinary tract infections and respiratory infections. Its prolonged half-life allows once-daily or less frequent dosing compared to short-acting sulfonamides. Like all sulfonamides, it inhibits dihydropteroate synthase to block bacterial folate synthesis.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Sulfadimethoxine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL62193.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5323.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Medical Disclaimer

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.