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Tiagabine

CHEMBL1027 Phase 4 معتمد Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
375.6 g/mol
LogP
2.7
Phase
4

This anticonvulsant medication is used as an add-on treatment for partial seizures in adults and children over the age of twelve. It works by blocking the reuptake of GABA, an inhibitory brain chemical, thereby reducing abnormal electrical activity in the brain. Seizures can paradoxically worsen in some patients who do not have epilepsy, so it is only recommended for this condition.

الوزن الجزيئي

375,6000 g/mol

LogP

2,70

TPSA

97,00 Ų

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Epilepsy Schizophrenia Generalized Anxiety Disorder

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Cc1ccsc1C(=CCCN1CCC[C@@H](C(=O)O)C1)c1sccc1C

                

                

                
                

                    
InChI

                    
InChI=1S/C20H25NO2S2/c1-14-7-11-24-18(14)17(19-15(2)8-12-25-19)6-4-10-21-9-3-5-16(13-21)20(22)23/h6-8,11-12,16H,3-5,9-10,13H2,1-2H3,(H,22,23)/t16-/m1/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C20H25NO2S2

                    

                    
                    

                        
HBD / HBA

                        
1 / 5

                    

                    
                    

                        
الروابط القابلة للدوران

                        
6

                    

                    
                    
                    

                        
الذرات الثقيلة

                        
25

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
الأسئلة الشائعة

                

                    
                    

                        
                        

                            
This anticonvulsant medication is used as an add-on treatment for partial seizures in adults and children over the age of twelve. It works by blocking the reuptake of GABA, an inhibitory brain chemical, thereby reducing abnormal electrical activity in the brain. Seizures can paradoxically worsen in some patients who do not have epilepsy, so it is only recommended for this condition.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Tiagabine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1027.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 60648.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
إخلاء المسؤولية الطبية

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.