Trospium Chloride

CHEMBL3084748 Phase 4 معتمد Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
428.0 g/mol
LogP
Phase
4

Trospium chloride is the chloride salt form of trospium, a quaternary ammonium antimuscarinic used for overactive bladder syndrome by selectively blocking M3 muscarinic receptors in bladder smooth muscle. It reduces detrusor overactivity, decreasing urinary urgency, frequency, and incontinence episodes. The quaternary ammonium structure minimizes blood-brain barrier penetration, offering a favorable CNS safety profile.

الوزن الجزيئي

428,0000 g/mol

TPSA

46,50 Ų

المجالات العلاجية

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

SVG PNG

Cite this structure


                        

Embed this structure


                        

SMILES

O=C(O[C@H]1C[C@H]2CC[C@@H](C1)[N+]21CCCC1)C(O)(c1ccccc1)c1ccccc1.[Cl-]

InChI

InChI=1S/C25H30NO3.ClH/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26;/h1-6,9-12,21-23,28H,7-8,13-18H2;1H/q+1;/p-1/t21-,22+,23+;

Molecular Formula

C25H30ClNO3

HBD / HBA

1 / 4

الروابط القابلة للدوران

5

الذرات الثقيلة

30

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

Trospium chloride is the chloride salt form of trospium, a quaternary ammonium antimuscarinic used for overactive bladder syndrome by selectively blocking M3 muscarinic receptors in bladder smooth muscle. It reduces detrusor overactivity, decreasing urinary urgency, frequency, and incontinence episodes. The quaternary ammonium structure minimizes blood-brain barrier penetration, offering a favorable CNS safety profile.

Yes, Trospium Chloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3084748. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5284631. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.