Trospium Chloride

CHEMBL3084748 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

428.0 g/mol

LogP

—

Phase

4

Trospium chloride is the chloride salt form of trospium, a quaternary ammonium antimuscarinic used for overactive bladder syndrome by selectively blocking M3 muscarinic receptors in bladder smooth muscle. It reduces detrusor overactivity, decreasing urinary urgency, frequency, and incontinence episodes. The quaternary ammonium structure minimizes blood-brain barrier penetration, offering a favorable CNS safety profile.

Molecular Weight

428.0000 g/mol

TPSA

46.50 Å²

Therapeutic Areas

Alzheimer's Disease Bipolar Disorder Chronic Obstructive Pulmonary Disease Obesity Schizophrenia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

Cite this structure

Embed this structure

SMILES

O=C(O[C@H]1C[C@H]2CC[C@@H](C1)[N+]21CCCC1)C(O)(c1ccccc1)c1ccccc1.[Cl-]

InChI

InChI=1S/C25H30NO3.ClH/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26;/h1-6,9-12,21-23,28H,7-8,13-18H2;1H/q+1;/p-1/t21-,22+,23+;

Molecular Formula

C25H30ClNO3

HBD / HBA

1 / 4

Rotatable Bonds

5

Heavy Atoms

30

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

Trospium chloride is the chloride salt form of trospium, a quaternary ammonium antimuscarinic used for overactive bladder syndrome by selectively blocking M3 muscarinic receptors in bladder smooth muscle. It reduces detrusor overactivity, decreasing urinary urgency, frequency, and incontinence episodes. The quaternary ammonium structure minimizes blood-brain barrier penetration, offering a favorable CNS safety profile.

Yes, Trospium Chloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3084748. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5284631. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

Looking for patient-friendly information?

Trospium Chloride on PillFYI

Structure

Quick Data

Formula: C25H30ClNO3
Synonyms: 2

External Links

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.