Therapeutic Index (TI)
TIThe ratio of the toxic dose to the therapeutic dose (TD50/ED50 or LD50/ED50). A narrow therapeutic index means small dose changes can cause toxicity or loss of efficacy, requiring close monitoring.
أمثلة
- Lithium (NTI drug)
- Warfarin (NTI drug)
- Digoxin (NTI drug)
هل تعلم؟
The ratio of the toxic dose to the therapeutic dose (TD50/ED50 or LD50/ED50). A narrow therapeutic index means small dose changes can cause toxicity or loss of efficacy, requiring close …