SCN9A (Sodium Channel Nav1.7)
SCN9A
Voltage-gated sodium channel preferentially expressed in nociceptive neurons.
الوظيفة
Gain-of-function mutations cause inherited pain disorders. Blocking reduces pain signaling.
الأدوية التي تؤثر على هذا الهدف
| الدواء | الفعل | أساسي |
|---|---|---|
| Valproic Acid | Blocker | نعم |
| Topiramate | Blocker | نعم |
| Phenytoin | Blocker | نعم |
| Gabapentin | Blocker | نعم |
| Pregabalin | Blocker | نعم |
| Lamotrigine | Blocker | نعم |
| Carbamazepine | Blocker | نعم |
| Furosemide | Inhibitor | نعم |
| Hydrochlorothiazide | Inhibitor | نعم |