Alprazolam vs Lorazepam

## Alprazolam vs Lorazepam: Overview

This comparison examines the pharmacological differences between **Alprazolam** and **Lorazepam**.

## Mechanism of Action

**Alprazolam**: High-potency benzodiazepine GABA-A receptor modulator.

**Lorazepam**: Intermediate-acting benzodiazepine enhancing GABA-A receptor chloride conductance.

## Pharmacokinetics

**Half-life**: Alprazolam — 6-12 hours; Lorazepam — 10-20 hours.

## Chemical Properties

**Molecular Formula**: Alprazolam — C17H13ClN4; Lorazepam — C15H10Cl2N2O2.

**Molecular Weight**: Alprazolam — 308.7650 g/mol; Lorazepam — 321.1580 g/mol.

**Type**: Alprazolam — Small molecule; Lorazepam — Small molecule.