Alprostadil vs Sildenafil

## Alprostadil vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Alprostadil** and **Sildenafil**.

## Mechanism of Action

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Alprostadil — N/A; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Alprostadil — N/A; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Alprostadil — N/A; Sildenafil — 474.5800 g/mol.

**Type**: Alprostadil — Small molecule; Sildenafil — Small molecule.