Aspirin vs Sildenafil

## Aspirin vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Aspirin** and **Sildenafil**.

## Mechanism of Action

**Aspirin**: Irreversibly inhibits cyclooxygenase-1 and -2.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Aspirin — 2-3 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Aspirin — C9H8O4; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Aspirin — 180.1580 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Aspirin — Small molecule; Sildenafil — Small molecule.