Atorvastatin vs Captopril

## Atorvastatin vs Captopril: Overview

This comparison examines the pharmacological differences between **Atorvastatin** and **Captopril**.

## Mechanism of Action

**Atorvastatin**: Competitive inhibitor of HMG-CoA reductase.

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

## Pharmacokinetics

**Half-life**: Atorvastatin — 14 hours; Captopril — 1.9 hours.

## Chemical Properties

**Molecular Formula**: Atorvastatin — C33H35FN2O5; Captopril — C9H15NO3S.

**Molecular Weight**: Atorvastatin — 558.6400 g/mol; Captopril — 217.2850 g/mol.

**Type**: Atorvastatin — Small molecule; Captopril — Small molecule.