Azithromycin vs Norfloxacin

## Azithromycin vs Norfloxacin: Overview

This comparison examines the pharmacological differences between **Azithromycin** and **Norfloxacin**.

## Mechanism of Action

**Azithromycin**: Binds 50S ribosomal subunit, inhibiting bacterial protein synthesis.

**Norfloxacin**: Second-generation fluoroquinolone inhibiting bacterial DNA gyrase and topoisomerase IV.

## Pharmacokinetics

**Half-life**: Azithromycin — 68 hours; Norfloxacin — 3-4 hours.

## Chemical Properties

**Molecular Formula**: Azithromycin — C38H72N2O12; Norfloxacin — C16H18FN3O3.

**Molecular Weight**: Azithromycin — 748.9840 g/mol; Norfloxacin — 319.3310 g/mol.

**Type**: Azithromycin — Small molecule; Norfloxacin — Small molecule.