Bisoprolol vs Hydrochlorothiazide

## Bisoprolol vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between **Bisoprolol** and **Hydrochlorothiazide**.

## Mechanism of Action

**Bisoprolol**: Highly selective beta-1 adrenergic receptor blocker reducing heart rate and myocardial contractility.

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Bisoprolol — 10-12 hours; Hydrochlorothiazide — 6-15 hours.

## Chemical Properties

**Molecular Formula**: Bisoprolol — C18H31NO4; Hydrochlorothiazide — C7H8ClN3O4S2.

**Molecular Weight**: Bisoprolol — 325.4470 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

**Type**: Bisoprolol — Small molecule; Hydrochlorothiazide — Small molecule.