Buprenorphine vs Oxycodone
Buprenorphine vs Oxycodone: Overview
This comparison examines the pharmacological differences between Buprenorphine and Oxycodone.
Mechanism of Action
Buprenorphine: Partial mu-opioid receptor agonist and kappa antagonist with high receptor affinity.
Oxycodone: Semisynthetic mu-opioid receptor agonist.
Pharmacokinetics
Half-life: Buprenorphine — 24-42 hours; Oxycodone — 3-5 hours.
Chemical Properties
Molecular Formula: Buprenorphine — C29H41NO4; Oxycodone — C18H21NO4.
Molecular Weight: Buprenorphine — 467.6430 g/mol; Oxycodone — 315.3640 g/mol.
Type: Buprenorphine — Small molecule; Oxycodone — Small molecule.