Bupropion vs Citalopram

Bupropion vs Citalopram: Overview

This comparison examines the pharmacological differences between Bupropion and Citalopram.

Mechanism of Action

Bupropion: Norepinephrine-dopamine reuptake inhibitor (NDRI).

Citalopram: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

Pharmacokinetics

Half-life: Bupropion — 21 hours; Citalopram — 35 hours.

Chemical Properties

Molecular Formula: Bupropion — C13H18ClNO; Citalopram — C20H21FN2O.

Molecular Weight: Bupropion — 239.7420 g/mol; Citalopram — 324.3920 g/mol.

Type: Bupropion — Small molecule; Citalopram — Small molecule.