Bupropion vs Fluoxetine

Bupropion vs Fluoxetine: Overview

This comparison examines the pharmacological differences between Bupropion and Fluoxetine.

Mechanism of Action

Bupropion: Norepinephrine-dopamine reuptake inhibitor (NDRI).

Fluoxetine: Selective serotonin reuptake inhibitor (SSRI).

Pharmacokinetics

Half-life: Bupropion — 21 hours; Fluoxetine — 1-3 days.

Chemical Properties

Molecular Formula: Bupropion — C13H18ClNO; Fluoxetine — C17H18F3NO.

Molecular Weight: Bupropion — 239.7420 g/mol; Fluoxetine — 309.3260 g/mol.

Type: Bupropion — Small molecule; Fluoxetine — Small molecule.