Canagliflozin vs Furosemide

Canagliflozin vs Furosemide: Overview

This comparison examines the pharmacological differences between Canagliflozin and Furosemide.

Mechanism of Action

Canagliflozin: Selective SGLT2 inhibitor reducing renal glucose reabsorption and lowering blood glucose.

Furosemide: Loop diuretic inhibiting Na-K-2Cl cotransporter.

Pharmacokinetics

Half-life: Canagliflozin — 10.6 hours; Furosemide — 2 hours.

Chemical Properties

Molecular Formula: Canagliflozin — C24H25FO5S; Furosemide — C12H11ClN2O5S.

Molecular Weight: Canagliflozin — 444.5170 g/mol; Furosemide — 330.7440 g/mol.

Type: Canagliflozin — Small molecule; Furosemide — Small molecule.