Candesartan vs Enalapril

Candesartan vs Enalapril: Overview

This comparison examines the pharmacological differences between Candesartan and Enalapril.

Mechanism of Action

Candesartan: Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.

Enalapril: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

Pharmacokinetics

Half-life: Candesartan — 9 hours; Enalapril — 11 hours.

Chemical Properties

Molecular Formula: Candesartan — C33H34N6O6; Enalapril — C20H28N2O5.

Molecular Weight: Candesartan — 610.6640 g/mol; Enalapril — 376.4470 g/mol.

Type: Candesartan — Small molecule; Enalapril — Small molecule.