Candesartan vs Irbesartan

Candesartan vs Irbesartan: Overview

This comparison examines the pharmacological differences between Candesartan and Irbesartan.

Mechanism of Action

Candesartan: Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.

Irbesartan: Selective non-competitive angiotensin II type 1 receptor antagonist.

Pharmacokinetics

Half-life: Candesartan — 9 hours; Irbesartan — 11-15 hours.

Chemical Properties

Molecular Formula: Candesartan — C33H34N6O6; Irbesartan — C25H28N6O.

Molecular Weight: Candesartan — 610.6640 g/mol; Irbesartan — 428.5320 g/mol.

Type: Candesartan — Small molecule; Irbesartan — Small molecule.