Captopril vs Celecoxib

Captopril vs Celecoxib: Overview

This comparison examines the pharmacological differences between Captopril and Celecoxib.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Celecoxib: Selective COX-2 inhibitor.

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Celecoxib — 11 hours.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Celecoxib — C17H14F3N3O2S.

Molecular Weight: Captopril — 217.2850 g/mol; Celecoxib — 381.3730 g/mol.

Type: Captopril — Small molecule; Celecoxib — Small molecule.