Captopril vs Diazepam

Captopril vs Diazepam: Overview

This comparison examines the pharmacological differences between Captopril and Diazepam.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Diazepam: Positive allosteric modulator of GABA-A receptors.

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Diazepam — 20-100 hours.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Diazepam — C16H13ClN2O.

Molecular Weight: Captopril — 217.2850 g/mol; Diazepam — 284.7400 g/mol.

Type: Captopril — Small molecule; Diazepam — Small molecule.