Captopril vs Escitalopram

Captopril vs Escitalopram: Overview

This comparison examines the pharmacological differences between Captopril and Escitalopram.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Escitalopram: S-enantiomer of citalopram; selective serotonin reuptake inhibitor.

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Escitalopram — 27-32 hours.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Escitalopram — C20H21FN2O.

Molecular Weight: Captopril — 217.2850 g/mol; Escitalopram — 324.3920 g/mol.

Type: Captopril — Small molecule; Escitalopram — Small molecule.