Captopril vs Fentanyl

Captopril vs Fentanyl: Overview

This comparison examines the pharmacological differences between Captopril and Fentanyl.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Fentanyl: Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Fentanyl — 2-4 hours.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Fentanyl — C22H28N2O.

Molecular Weight: Captopril — 217.2850 g/mol; Fentanyl — 336.4700 g/mol.

Type: Captopril — Small molecule; Fentanyl — Small molecule.