Captopril vs Lovastatin

## Captopril vs Lovastatin: Overview

This comparison examines the pharmacological differences between **Captopril** and **Lovastatin**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Lovastatin**: First naturally derived statin; prodrug hydrolyzed to active beta-hydroxy acid inhibiting HMG-CoA reductase.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Lovastatin — 2-3 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Lovastatin — C24H36O5.

**Molecular Weight**: Captopril — 217.2850 g/mol; Lovastatin — 404.5390 g/mol.

**Type**: Captopril — Small molecule; Lovastatin — Small molecule.