Captopril vs Memantine

Captopril vs Memantine: Overview

This comparison examines the pharmacological differences between Captopril and Memantine.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Memantine: Non-competitive NMDA receptor antagonist.

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Memantine — 60-80 hours.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Memantine — C12H21N.

Molecular Weight: Captopril — 217.2850 g/mol; Memantine — 179.3080 g/mol.

Type: Captopril — Small molecule; Memantine — Small molecule.