Captopril vs Metronidazole

Captopril vs Metronidazole: Overview

This comparison examines the pharmacological differences between Captopril and Metronidazole.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Metronidazole: Forms cytotoxic free radicals that damage bacterial DNA.

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Metronidazole — 8 hours.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Metronidazole — C6H9N3O3.

Molecular Weight: Captopril — 217.2850 g/mol; Metronidazole — 171.1540 g/mol.

Type: Captopril — Small molecule; Metronidazole — Small molecule.