Captopril vs Paroxetine

## Captopril vs Paroxetine: Overview

This comparison examines the pharmacological differences between **Captopril** and **Paroxetine**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Paroxetine**: Potent selective serotonin reuptake inhibitor with additional muscarinic and NE reuptake inhibition.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Paroxetine — 21 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Paroxetine — C19H20FNO3.

**Molecular Weight**: Captopril — 217.2850 g/mol; Paroxetine — 329.3730 g/mol.

**Type**: Captopril — Small molecule; Paroxetine — Small molecule.