Captopril vs Paroxetine

Captopril vs Paroxetine: Overview

This comparison examines the pharmacological differences between Captopril and Paroxetine.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Paroxetine: Potent selective serotonin reuptake inhibitor with additional muscarinic and NE reuptake inhibition.

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Paroxetine — 21 hours.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Paroxetine — C19H20FNO3.

Molecular Weight: Captopril — 217.2850 g/mol; Paroxetine — 329.3730 g/mol.

Type: Captopril — Small molecule; Paroxetine — Small molecule.