Captopril vs Sertraline

Captopril vs Sertraline: Overview

This comparison examines the pharmacological differences between Captopril and Sertraline.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Sertraline: Selective serotonin reuptake inhibitor (SSRI).

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Sertraline — 26 hours.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Sertraline — C17H17Cl2N.

Molecular Weight: Captopril — 217.2850 g/mol; Sertraline — 306.2290 g/mol.

Type: Captopril — Small molecule; Sertraline — Small molecule.