Captopril vs Valsartan
Captopril vs Valsartan: Overview
This comparison examines the pharmacological differences between Captopril and Valsartan.
Mechanism of Action
Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.
Valsartan: Angiotensin II type 1 receptor blocker.
Pharmacokinetics
Half-life: Captopril — 1.9 hours; Valsartan — 6 hours.
Chemical Properties
Molecular Formula: Captopril — C9H15NO3S; Valsartan — C24H29N5O3.
Molecular Weight: Captopril — 217.2850 g/mol; Valsartan — 435.5190 g/mol.
Type: Captopril — Small molecule; Valsartan — Small molecule.