Cephalexin vs Fluconazole

Cephalexin vs Fluconazole: Overview

This comparison examines the pharmacological differences between Cephalexin and Fluconazole.

Mechanism of Action

Cephalexin: First-generation cephalosporin inhibiting cell wall synthesis.

Fluconazole: Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase).

Pharmacokinetics

Half-life: Cephalexin — 0.5-1.2 hours; Fluconazole — 30 hours.

Chemical Properties

Molecular Formula: Cephalexin — C16H17N3O4S; Fluconazole — C13H12F2N6O.

Molecular Weight: Cephalexin — 347.3890 g/mol; Fluconazole — 306.2710 g/mol.

Type: Cephalexin — Small molecule; Fluconazole — Small molecule.