Cephalexin vs Trimethoprim

Cephalexin vs Trimethoprim: Overview

This comparison examines the pharmacological differences between Cephalexin and Trimethoprim.

Mechanism of Action

Cephalexin: First-generation cephalosporin inhibiting cell wall synthesis.

Trimethoprim: Dihydrofolate reductase inhibitor (bacterial selective).

Pharmacokinetics

Half-life: Cephalexin — 0.5-1.2 hours; Trimethoprim — 8-10 hours.

Chemical Properties

Molecular Formula: Cephalexin — C16H17N3O4S; Trimethoprim — C14H18N4O3.

Molecular Weight: Cephalexin — 347.3890 g/mol; Trimethoprim — 290.3180 g/mol.

Type: Cephalexin — Small molecule; Trimethoprim — Small molecule.