Cetirizine vs Hydrochlorothiazide
Cetirizine vs Hydrochlorothiazide: Overview
This comparison examines the pharmacological differences between Cetirizine and Hydrochlorothiazide.
Mechanism of Action
Cetirizine: Second-generation H1 antihistamine.
Hydrochlorothiazide: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.
Pharmacokinetics
Half-life: Cetirizine — 6.5-10 hours; Hydrochlorothiazide — 6-15 hours.
Chemical Properties
Molecular Formula: Cetirizine — C21H25ClN2O3; Hydrochlorothiazide — C7H8ClN3O4S2.
Molecular Weight: Cetirizine — 388.8900 g/mol; Hydrochlorothiazide — 297.7400 g/mol.
Type: Cetirizine — Small molecule; Hydrochlorothiazide — Small molecule.