Citalopram vs Duloxetine
Citalopram vs Duloxetine: Overview
This comparison examines the pharmacological differences between Citalopram and Duloxetine.
Mechanism of Action
Citalopram: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.
Duloxetine: Serotonin-norepinephrine reuptake inhibitor (SNRI).
Pharmacokinetics
Half-life: Citalopram — 35 hours; Duloxetine — 12 hours.
Chemical Properties
Molecular Formula: Citalopram — C20H21FN2O; Duloxetine — C18H19NOS.
Molecular Weight: Citalopram — 324.3920 g/mol; Duloxetine — 297.4150 g/mol.
Type: Citalopram — Small molecule; Duloxetine — Small molecule.