Citalopram vs Pregabalin

Citalopram vs Pregabalin: Overview

This comparison examines the pharmacological differences between Citalopram and Pregabalin.

Mechanism of Action

Citalopram: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

Pregabalin: Binds alpha-2-delta subunit of voltage-gated calcium channels.

Pharmacokinetics

Half-life: Citalopram — 35 hours; Pregabalin — 6.3 hours.

Chemical Properties

Molecular Formula: Citalopram — C20H21FN2O; Pregabalin — C8H17NO2.

Molecular Weight: Citalopram — 324.3920 g/mol; Pregabalin — 159.2260 g/mol.

Type: Citalopram — Small molecule; Pregabalin — Small molecule.