Citalopram vs Trazodone

Citalopram vs Trazodone: Overview

This comparison examines the pharmacological differences between Citalopram and Trazodone.

Mechanism of Action

Citalopram: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

Trazodone: Serotonin antagonist and reuptake inhibitor (SARI).

Pharmacokinetics

Half-life: Citalopram — 35 hours; Trazodone — 5-9 hours.

Chemical Properties

Molecular Formula: Citalopram — C20H21FN2O; Trazodone — C19H22ClN5O.

Molecular Weight: Citalopram — 324.3920 g/mol; Trazodone — 371.8640 g/mol.

Type: Citalopram — Small molecule; Trazodone — Small molecule.