Citalopram vs Upadacitinib

Citalopram vs Upadacitinib: Overview

This comparison examines the pharmacological differences between Citalopram and Upadacitinib.

Mechanism of Action

Citalopram: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

Upadacitinib: Selective JAK1 inhibitor reducing signaling from cytokines implicated in autoimmune diseases.

Pharmacokinetics

Half-life: Citalopram — 35 hours; Upadacitinib — 9-14 hours.

Chemical Properties

Molecular Formula: Citalopram — C20H21FN2O; Upadacitinib — C17H19F3N6O.

Molecular Weight: Citalopram — 324.3920 g/mol; Upadacitinib — 380.3700 g/mol.

Type: Citalopram — Small molecule; Upadacitinib — Small molecule.