Cyclosporine vs Trimethoprim

Cyclosporine vs Trimethoprim: Overview

This comparison examines the pharmacological differences between Cyclosporine and Trimethoprim.

Mechanism of Action

Cyclosporine: Calcineurin inhibitor suppressing T-cell activation.

Trimethoprim: Dihydrofolate reductase inhibitor (bacterial selective).

Pharmacokinetics

Half-life: Cyclosporine — 6-12 hours; Trimethoprim — 8-10 hours.

Chemical Properties

Molecular Formula: Cyclosporine — C62H111N11O12; Trimethoprim — C14H18N4O3.

Molecular Weight: Cyclosporine — 1202.6100 g/mol; Trimethoprim — 290.3180 g/mol.

Type: Cyclosporine — Protein; Trimethoprim — Small molecule.