Dapagliflozin vs Enalapril

Dapagliflozin vs Enalapril: Overview

This comparison examines the pharmacological differences between Dapagliflozin and Enalapril.

Mechanism of Action

Dapagliflozin: Selective SGLT2 inhibitor reducing renal glucose and sodium reabsorption.

Enalapril: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

Pharmacokinetics

Half-life: Dapagliflozin — 12.9 hours; Enalapril — 11 hours.

Chemical Properties

Molecular Formula: Dapagliflozin — C21H25ClO6; Enalapril — C20H28N2O5.

Molecular Weight: Dapagliflozin — 408.8730 g/mol; Enalapril — 376.4470 g/mol.

Type: Dapagliflozin — Small molecule; Enalapril — Small molecule.