Dapagliflozin vs Furosemide

Dapagliflozin vs Furosemide: Overview

This comparison examines the pharmacological differences between Dapagliflozin and Furosemide.

Mechanism of Action

Dapagliflozin: Selective SGLT2 inhibitor reducing renal glucose and sodium reabsorption.

Furosemide: Loop diuretic inhibiting Na-K-2Cl cotransporter.

Pharmacokinetics

Half-life: Dapagliflozin — 12.9 hours; Furosemide — 2 hours.

Chemical Properties

Molecular Formula: Dapagliflozin — C21H25ClO6; Furosemide — C12H11ClN2O5S.

Molecular Weight: Dapagliflozin — 408.8730 g/mol; Furosemide — 330.7440 g/mol.

Type: Dapagliflozin — Small molecule; Furosemide — Small molecule.