Dexamethasone vs Tacrolimus

## Dexamethasone vs Tacrolimus: Overview

This comparison examines the pharmacological differences between **Dexamethasone** and **Tacrolimus**.

## Mechanism of Action

**Dexamethasone**: Potent synthetic glucocorticoid.

**Tacrolimus**: Calcineurin inhibitor binding FKBP12; suppresses IL-2 transcription.

## Pharmacokinetics

**Half-life**: Dexamethasone — 36-54 hours; Tacrolimus — 12 hours.

## Chemical Properties

**Molecular Formula**: Dexamethasone — C22H29FO5; Tacrolimus — C44H69NO12.

**Molecular Weight**: Dexamethasone — 392.4610 g/mol; Tacrolimus — 804.0180 g/mol.

**Type**: Dexamethasone — Small molecule; Tacrolimus — Small molecule.