Digoxin vs Duloxetine

Digoxin vs Duloxetine: Overview

This comparison examines the pharmacological differences between Digoxin and Duloxetine.

Mechanism of Action

Digoxin: Inhibits Na+/K+-ATPase, increasing intracellular calcium.

Duloxetine: Serotonin-norepinephrine reuptake inhibitor (SNRI).

Pharmacokinetics

Half-life: Digoxin — 36-48 hours; Duloxetine — 12 hours.

Chemical Properties

Molecular Formula: Digoxin — C41H64O14; Duloxetine — C18H19NOS.

Molecular Weight: Digoxin — 780.9430 g/mol; Duloxetine — 297.4150 g/mol.

Type: Digoxin — Small molecule; Duloxetine — Small molecule.