Digoxin vs Lovastatin

Digoxin vs Lovastatin: Overview

This comparison examines the pharmacological differences between Digoxin and Lovastatin.

Mechanism of Action

Digoxin: Inhibits Na+/K+-ATPase, increasing intracellular calcium.

Lovastatin: First naturally derived statin; prodrug hydrolyzed to active beta-hydroxy acid inhibiting HMG-CoA reductase.

Pharmacokinetics

Half-life: Digoxin — 36-48 hours; Lovastatin — 2-3 hours.

Chemical Properties

Molecular Formula: Digoxin — C41H64O14; Lovastatin — C24H36O5.

Molecular Weight: Digoxin — 780.9430 g/mol; Lovastatin — 404.5390 g/mol.

Type: Digoxin — Small molecule; Lovastatin — Small molecule.