Diphenhydramine vs Doxycycline

## Diphenhydramine vs Doxycycline: Overview

This comparison examines the pharmacological differences between **Diphenhydramine** and **Doxycycline**.

## Mechanism of Action

**Diphenhydramine**: First-generation H1 antihistamine with anticholinergic properties.

**Doxycycline**: Inhibits bacterial protein synthesis by binding 30S ribosomal subunit.

## Pharmacokinetics

**Half-life**: Diphenhydramine — 2-8 hours; Doxycycline — 18-22 hours.

## Chemical Properties

**Molecular Formula**: Diphenhydramine — C17H21NO; Doxycycline — C22H24N2O8.

**Molecular Weight**: Diphenhydramine — 255.3550 g/mol; Doxycycline — 444.4350 g/mol.

**Type**: Diphenhydramine — Small molecule; Doxycycline — Small molecule.