Diphenhydramine vs Prednisone

## Diphenhydramine vs Prednisone: Overview

This comparison examines the pharmacological differences between **Diphenhydramine** and **Prednisone**.

## Mechanism of Action

**Diphenhydramine**: First-generation H1 antihistamine with anticholinergic properties.

**Prednisone**: Synthetic corticosteroid; suppresses inflammation via glucocorticoid receptor.

## Pharmacokinetics

**Half-life**: Diphenhydramine — 2-8 hours; Prednisone — 2-3 hours.

## Chemical Properties

**Molecular Formula**: Diphenhydramine — C17H21NO; Prednisone — C21H26O5.

**Molecular Weight**: Diphenhydramine — 255.3550 g/mol; Prednisone — 358.4280 g/mol.

**Type**: Diphenhydramine — Small molecule; Prednisone — Small molecule.