Diphenhydramine vs Ranitidine

## Diphenhydramine vs Ranitidine: Overview

This comparison examines the pharmacological differences between **Diphenhydramine** and **Ranitidine**.

## Mechanism of Action

**Diphenhydramine**: First-generation H1 antihistamine with anticholinergic properties.

**Ranitidine**: Competitive H2 receptor antagonist.

## Pharmacokinetics

**Half-life**: Diphenhydramine — 2-8 hours; Ranitidine — 2-3 hours.

## Chemical Properties

**Molecular Formula**: Diphenhydramine — C17H21NO; Ranitidine — C13H22N4O3S.

**Molecular Weight**: Diphenhydramine — 255.3550 g/mol; Ranitidine — 314.4050 g/mol.

**Type**: Diphenhydramine — Small molecule; Ranitidine — Small molecule.