Doxycycline vs Fluconazole

Doxycycline vs Fluconazole: Overview

This comparison examines the pharmacological differences between Doxycycline and Fluconazole.

Mechanism of Action

Doxycycline: Inhibits bacterial protein synthesis by binding 30S ribosomal subunit.

Fluconazole: Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase).

Pharmacokinetics

Half-life: Doxycycline — 18-22 hours; Fluconazole — 30 hours.

Chemical Properties

Molecular Formula: Doxycycline — C22H24N2O8; Fluconazole — C13H12F2N6O.

Molecular Weight: Doxycycline — 444.4350 g/mol; Fluconazole — 306.2710 g/mol.

Type: Doxycycline — Small molecule; Fluconazole — Small molecule.