Doxycycline vs Vancomycin

Doxycycline vs Vancomycin: Overview

This comparison examines the pharmacological differences between Doxycycline and Vancomycin.

Mechanism of Action

Doxycycline: Inhibits bacterial protein synthesis by binding 30S ribosomal subunit.

Vancomycin: Glycopeptide antibiotic inhibiting cell wall synthesis by binding D-Ala-D-Ala terminus of peptidoglycan precursors.

Pharmacokinetics

Half-life: Doxycycline — 18-22 hours; Vancomycin — 4-6 hours.

Chemical Properties

Molecular Formula: Doxycycline — C22H24N2O8; Vancomycin — C66H75Cl2N9O24.

Molecular Weight: Doxycycline — 444.4350 g/mol; Vancomycin — 1449.2500 g/mol.

Type: Doxycycline — Small molecule; Vancomycin — Small molecule.