Duloxetine vs Gabapentin

Duloxetine vs Gabapentin: Overview

This comparison examines the pharmacological differences between Duloxetine and Gabapentin.

Mechanism of Action

Duloxetine: Serotonin-norepinephrine reuptake inhibitor (SNRI).

Gabapentin: Binds alpha-2-delta subunit of voltage-gated calcium channels.

Pharmacokinetics

Half-life: Duloxetine — 12 hours; Gabapentin — 5-7 hours.

Chemical Properties

Molecular Formula: Duloxetine — C18H19NOS; Gabapentin — C9H17NO2.

Molecular Weight: Duloxetine — 297.4150 g/mol; Gabapentin — 171.2370 g/mol.

Type: Duloxetine — Small molecule; Gabapentin — Small molecule.