Duloxetine vs Sitagliptin

## Duloxetine vs Sitagliptin: Overview

This comparison examines the pharmacological differences between **Duloxetine** and **Sitagliptin**.

## Mechanism of Action

**Duloxetine**: Serotonin-norepinephrine reuptake inhibitor (SNRI).

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

## Pharmacokinetics

**Half-life**: Duloxetine — 12 hours; Sitagliptin — 12.4 hours.

## Chemical Properties

**Molecular Formula**: Duloxetine — C18H19NOS; Sitagliptin — C16H15F6N5O.

**Molecular Weight**: Duloxetine — 297.4150 g/mol; Sitagliptin — 407.3140 g/mol.

**Type**: Duloxetine — Small molecule; Sitagliptin — Small molecule.