Duloxetine vs Venlafaxine

Duloxetine vs Venlafaxine: Overview

This comparison examines the pharmacological differences between Duloxetine and Venlafaxine.

Mechanism of Action

Duloxetine: Serotonin-norepinephrine reuptake inhibitor (SNRI).

Venlafaxine: Serotonin-norepinephrine reuptake inhibitor (SNRI).

Pharmacokinetics

Half-life: Duloxetine — 12 hours; Venlafaxine — 5 hours.

Chemical Properties

Molecular Formula: Duloxetine — C18H19NOS; Venlafaxine — C17H27NO2.

Molecular Weight: Duloxetine — 297.4150 g/mol; Venlafaxine — 277.4020 g/mol.

Type: Duloxetine — Small molecule; Venlafaxine — Small molecule.