Durvalumab vs Methylprednisolone
Durvalumab vs Methylprednisolone: Overview
This comparison examines the pharmacological differences between Durvalumab and Methylprednisolone.
Mechanism of Action
Durvalumab: Human IgG1 kappa anti-PD-L1 monoclonal antibody blocking PD-L1 binding to PD-1 and CD80.
Methylprednisolone: Intermediate-acting synthetic glucocorticoid.
Pharmacokinetics
Half-life: Durvalumab — 17 days; Methylprednisolone — 18-36 hours.
Chemical Properties
Molecular Formula: Methylprednisolone — C22H30O5.
Molecular Weight: Methylprednisolone — 374.4710 g/mol.
Type: Durvalumab — Antibody; Methylprednisolone — Small molecule.